GLUCORYL-MV2

Introduction About GLUCORYL MV 2/0.2MG TABLET GLUCORYL MV 2/0.2MG TABLET is used in adults to manage type 2 diabetes mellitus when diet, exercise, and single-agent or second-line therapy with two drugs are insufficient to adequately control blood sugar levels. It contains a combination of three medicines namely, Glimepiride, Metformin and Voglibose, which works by making your body absorb circulating blood glucose levels. Take GLUCORYL MV 2/0.2MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. GLUCORYL MV 2/0.2MG TABLET is not recommended for use in patients allergic to glimepiride, metformin, voglibose, and/or other sulfonylureas or sulphonamides. It is also not recommended for use in patients with acute conditions (such as dehydration or severe infection), severe ketosis (a severe complication of diabetes), severe trauma, lung problems (such as acute or chronic respiratory failure), heart problems (such as acute or chronic cardiac failure or recent myocardial infarction), and/or severe kidney or liver problems. Before taking GLUCORYL MV 2/0.2MG TABLET, inform your doctor if you recently had trauma and/or have febrile infections, fever, uncontrolled diabetes, hypothyroidism (underactive thyroid), chronic intestinal disease, fever, or other kidney or liver problems. GLUCORYL MV 2/0.2MG TABLET is not recommended for use in pregnant and breastfeeding women since it may cause harm to the developing fetus or nursing child. GLUCORYL MV 2/0.2MG TABLET is also not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 75 years or older) after consulting the doctor. The most common side effects of GLUCORYL MV 2/0.2MG TABLET are nausea and vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and/or hypoglycemia (low blood sugar). Uses Of GLUCORYL MV 2/0.2MG TABLET Type II diabetes mellitus How GLUCORYL MV 2/0.2MG TABLET Works GLUCORYL MV 2/0.2MG TABLET contains a combination of three medicines namely, glimepiride, metformin, and voglibose. Each of these drugs works in a different way to help lower blood sugar: Glimepiride: It stimulates the pancreas to release more insulin, which helps lower blood sugar by allowing cells to take in glucose. Metformin: It decreases the amount of glucose produced by the liver and improves the sensitivity of muscle cells to insulin, allowing them to use glucose more effectively. Voglibose: It inhibits enzymes in the gut that break down carbohydrates into glucose, slowing down the absorption of sugar from food. Together, these actions help control blood sugar levels throughout the day by improving insulin secretion, reducing glucose production, and slowing sugar absorption. How to use GLUCORYL MV 2/0.2MG TABLET Take GLUCORYL MV 2/0.2MG TABLET under medical supervision. It can be taken once or twice daily with meals, depending on your doctor’s advice Taking it with food helps reduce stomach upset and ensures proper absorption of the medication. The tablet should be swallowed whole with water. Do not crush, chew, or break the tablet as this can affect how the medication is absorbed. Since glimepiride stimulates insulin release, make sure to eat meals regularly to avoid hypoglycemia (low blood sugar). Do not adjust the dose or stop taking the medication without consulting your healthcare provider. Always follow your doctor's specific instructions, and regularly monitor your blood sugar levels as advised. Side Effects Of GLUCORYL MV 2/0.2MG TABLET Common Side Effects of GLUCORYL MV 2/0.2MG TABLET: Nausea, vomiting, diarrhea, abdominal pain, and loss of appetite Metallic taste Hypoglycaemia (low blood sugar) Stop taking GLUCORYL MV 2/0.2MG TABLET and contact your doctor immediately if you experience any of the following side effects: Severe hypoglycemia (very low blood sugar level) Signs of lactic acidosis (lactic acid built up in the bloodstream) such as exhaustion or extreme fatigue, body weakness, diarrhea, and/or headache Warning & Precautions Pregnancy Contraindicated GLUCORYL MV 2/0.2MG TABLET is not recommended for use during pregnancy since it may cause harm to the fetus. Breastfeeding Contraindicated GLUCORYL MV 2/0.2MG TABLET is not recommended for use in breastfeeding women since the medicine may pass through breast milk and may cause harm to the nursing child. Driving and Using Machines Use with Caution Do not drive or operate any machines if you experience impaired alertness or reactions (due to hypoglycemia) while taking GLUCORYL MV 2/0.2MG TABLET. Alcohol Contraindicated Do not consume alcohol while taking GLUCORYL MV 2/0.2MG TABLET since it may reduce your blood sugar level. Kidney Consult your doctor GLUCORYL MV 2/0.2MG TABLET is not recommended in patients with severe renal failure. It should be used with caution in patients with other kidney diseases. Liver Consult your doctor GLUCORYL MV 2/0.2MG TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with other liver diseases. Allergy Contraindicated Do not take GLUCORYL MV 2/0.2MG TABLET if you are allergic to glimepiride, metformin, voglibose, other sulfonylureas/sulphonamides, and/or any other ingredients of this medicine. Lungs Contraindicated GLUCORYL MV 2/0.2MG TABLET is not recommended for use in patients with lung problems such as acute or chronic respiratory failure. Heart Disease Contraindicated GLUCORYL MV 2/0.2MG TABLET) is not recommended in patients with heart problems such as acute or chronic cardiac failure or recent myocardial infarction. Use In Pediatrics Contraindicated GLUCORYL MV 2/0.2MG TABLET is not recommended for use in children and adolescents (aged below 18 years) since the safety and effectiveness of the medicine are not established. Use In Geriatrics Use with Caution GLUCORYL MV 2/0.2MG TABLET should be used with caution in elderly patients (aged 65 years and above). Others GLUCORYL MV 2/0.2MG TABLET is not recommended for use if you: Suffer from any acute type of metabolic acidosis (the buildup of excess acid in the body), such as lactic acidosis, diabetic ketoacidosis, and/or diabetic precoma Suffer from acute conditions such as dehydration, severe infection, and shock Have severe ketosis (a severe complication of diabetes) Are in a state of diabetic coma Had severe infections before or after the operation Had severe trauma Have gastrointestinal obstruction Before taking GLUCORYL MV 2/0.2MG TABLET, inform your doctor if you: Recently had trauma Had or scheduled for any surgery Suffer from febrile infections, fever, and/or uncontrolled diabetes Are undernourished and/or have irregular mealtimes or skipped meals Suffer from an imbalance between physical exertion and carbohydrate intake Have hypothyroidism (underactive thyroid) Have a history of laparotomy (a surgical incision done into the abdominal cavity for diagnosing a condition) and/or ileus (interrupted movement of the intestines) Suffer from chronic intestinal disease (accompanied by disturbances in digestion and absorption) Suffer from fever Interactions A. Drug-Drug interactions: Before taking GLUCORYL MV 2/0.2MG TABLET, inform your doctor if you are taking any of the following medicines: Antibacterials (Ex. rifampicin, ciprofloxacin, clarithromycin, sulfacetamide, minocycline, and chloramphenicol) Antifungals (Ex. fluconazole, isavuconazole, and miconazole) Oral antidiabetics and insulin (medicines used to manage high blood sugar) Ex. glipizide, glyburide diazoxide Anticancer (Ex. cyclophosphamide, trofosfamide, vandetanib, crizotinib, olaparib) Disopyramide (medicine used to manage an irregular heartbeat) Fenyramidol (a medicine used to relax muscles) Pentoxifylline (a medicine used to improve blood flow through the arteries) Medicine used to manage joint pain (Ex. phenylbutazone, oxyphenbutazone, and probenecid sulfinpyrazone) Corticosteroids (Ex. prednisolone, methylprednisolone) Diuretics (Ex. Furosemide) Laxatives (Ex. Bisacodyl) Phenytoin and fenfluramine (medicines used to manage seizures) Dolutegravir (a medicine used to manage HIV infection) Antidepressants (Ex. phenelzine, selegiline) alpha blockers (Ex. doxazosin, prazosin) Anticoagulants (Ex. Warfarin) Overdosage: If you or anyone else accidentally takes too much of GLUCORYL MV 2/0.2MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are hypoglycemia (low blood sugar), lactic acidosis, pancreatitis (inflammation of the pancreas), abdominal discomfort, and/or diarrhea.