NAXDOM 500

INTRODUCTION ABOUT NAXDOM 500MG TABLET NAXDOM 500MG TABLET is a combination of Domperidone and Naproxen, which belong to the groups of medicines called antiemetics and NSAIDs (non-steroidal anti-inflammatory drugs), respectively. It is used to manage the symptoms of migraine, menstrual migraine, and chronic daily headaches associated with nausea and vomiting. A migraine is a recurring headache that often involves one side of the head and causes severe pain that is pulsating or throbbing and is accompanied by nausea, weakness, and sensitivity to sound and light. NAXDOM 500MG TABLET is not recommended in patients with severe liver, kidney, or heart problems, stomach ulcers, bleeding in the stomach or intestine, intestinal tears, or pituitary gland tumours. NAXDOM 500MG TABLET should be taken with caution in patients with lung disease, diabetes, high cholesterol, systemic lupus erythematosus, a blood clotting disorder, a history of gastrointestinal diseases, and a habit of drinking or smoking. NAXDOM 500MG TABLET is not recommended for use during pregnancy, while breastfeeding, or in children less than 5 years old. It should be used with caution in elderly patients (those over the age of 60). The common side effect of taking NAXDOM 500MG TABLET may include dry mouth. Consult your doctor immediately if your symptoms get worse or persist. USES OF NAXDOM 500MG TABLET Manage symptoms of migraine menstrual migraine chronic daily headache HOW NAXDOM 500MG TABLET WORKS NAXDOM 500MG TABLET effectively manages migraine, which is commonly associated with nausea and vomiting, by blocking the centres in the brain and stomach that regulate nausea and vomiting. It also increases the contractions and movements in the stomach. NAXDOM 500MG TABLET stops the pain pathways and reduces the release of substances (prostaglandins) that cause inflammation, thus decreasing pain and inflammation. DIRECTIONS FOR USE Take NAXDOM 500MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of NAXDOM 500MG TABLET for you depending on your age, body weight and disease condition. SIDE EFFECTS OF NAXDOM 500MG TABLET COMMON dry mouth UNCOMMON decreased sexual drive in men feeling anxious, drowsy and weak headache diarrhoea itchy skin pain or tenderness in breasts RARE Stop taking NAXDOM 500MG TABLET and talk to your doctor if you experience any of the following side effects: swelling of the hands, feet, ankles, face, lips or throat which may lead to difficulty in swallowing or breathing an itchy, lumpy rash (hives) or nettle rash (urticaria) any uncontrolled movements which include unusual movements of the tongue, irregular eye movements, and abnormal posture such as a twisted neck, muscle stiffness, and trembling very fast or unusual heartbeat a fit or seizure HOW TO MANAGE SIDE EFFECTS Headache: Try to rest and relax. Do not involve yourself in exertive activities. Apply a pain-relieving balm on your forehead. Diarrhoea: Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Drowsiness: Take adequate sleep. Do not involve in rigorous activities. Do not interfere with your sleep cycle. Talk to your doctor if the symptom doesn’t improve. WARNING & PRECAUTIONS PREGNANCY NAXDOM 500MG TABLET is not recommended for use in pregnant women during the first 6 months of pregnancy. NAXDOM 500MG TABLET must not be used during the last 3 months of pregnancy. Consult your doctor before taking it. BREASTFEEDING NAXDOM 500MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking it. DRIVING AND USING MACHINES Do not drive or operate any machines if you feel drowsy, dizzy, tired or have blurred vision after taking NAXDOM 500MG TABLET. KIDNEY NAXDOM 500MG TABLET is not recommended in patients with severe kidney disease. Consult your doctor before taking NAXDOM 500MG TABLET. LIVER NAXDOM 500MG TABLET is not recommended in patients with severe liver disease. Consult your doctor before taking it. ALLERGY Do not take NAXDOM 500MG TABLET if you are allergic to Domperidone or Naproxen. LUNGS NAXDOM 500MG TABLET should be used with caution in patients with lung diseases such as asthma, other breathing problems or nasal polyps. Consult your doctor before taking it. HEART DISEASE NAXDOM 500MG TABLET not recommended in patients with severe heart disease such as heart failure, prolonged QT corrected interval. It should be used with caution in patients having a stroke or high blood pressure. Consult your doctor before taking NAXDOM 500MG TABLET. OTHERS NAXDOM 500MG TABLET is not recommended for use if you: have stomach or duodenal ulcers have bleeding in the stomach or intestines have a blockage or tear in the intestine have a tumour of the pituitary gland Before taking NAXDOM 500MG TABLET tell your doctor if you: have a history of disorders of the stomach or bowel (ulcerative colitis, Crohn’s disease) have diabetes have a habit of smoking have systemic lupus erythematosus or other connective tissue disorder have a blood clotting disorder Use in paediatrics: NAXDOM 500MG TABLET is not recommended for use in children under 5 years of age. Consult your doctor before taking NAXDOM 500MG TABLET.  Use in geriatrics: NAXDOM 500MG TABLET should be used with caution in elderly patients (above 60 years of age). Consult your doctor for advice. INTERACTIONS A. Drug–Drug Interactions: Inform your physician if you are taking any of the following drugs before taking NAXDOM 500MG TABLET: medicines used to manage heart problems, high blood pressure (Ex. amiodarone, dronedarone, quinidine, disopyramide, captopril, ramipril, losartan, candesartan, dofetilide, sotalol, diltiazem, verapamil) medicines used in the management of psychoses (Ex. haloperidol, pimozide, sertindole), depression (Ex. citalopram, escitalopram), mental illness (Ex. lithium), epilepsy (Ex. phenytoin) medicines used to manage gastrointestinal disorders (Ex. cisapride, dolasetron, prucalopride), antacids (Ex. aluminium hydroxide gel) medicines used to manage bacterial infections (Ex. erythromycin, clarithromycin, ciprofloxacin, telithromycin, moxifloxacin, pentamidine) medicines used in the management of cancer (Ex. toremifene, methotrexate, vandetanib, vincamine) Overdosage: If you or anyone else accidentally takes too much NAXDOM 500MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdoes of NAXDOM 500MG TABLET can cause headaches, nausea, vomiting, sleepiness, confusion, heartburn, fainting, diarrhoea, disorientation, stomach or intestine bleeding, unconsciousness, drowsiness, dizziness, ringing or buzzing sensation in the ears, fits and excitation, unusual eye movements, unusual tongue movements, or abnormal posture (such as a twisted neck).  SYNOPSIS Drug :   Domperidone, Naproxen Pharmacological Category :   NSAIDs, Antiemetics Therapeutic Indication :   Migraine, Menstrual migraine and Chronic daily headache Dosage Forms :   Tablet MORE INFORMATION Keep NAXDOM 500MG TABLET out of reach from children Store below 25°C FAQs ABOUT NAXDOM 500MG TABLET Q: Does NAXDOM 500MG TABLET make you feel sleepy? A: Yes. NAXDOM 500MG TABLET may cause sleepiness, dizziness, fatigue, or blurred vision. Therefore, it is advised not to drive or use any machines if you feel any of the above side effects. Q: Is NAXDOM 500MG TABLET safe for use by pregnant and breastfeeding women? A: NAXDOM 500MG TABLET is not recommended for pregnant women in the first 6 months of pregnancy, and it must not be taken during the last 3 months. NAXDOM 500MG TABLET is not advised for breastfeeding women as it may pass through the milk. Consult with your doctor. Q: Does NAXDOM 500MG TABLET help with migraine? A: There is no permanent manage for migraine. NAXDOM 500MG TABLET is used to manage the symptoms of migraine, which could be nausea, weakness, and sensitivity to sound and light. Consult with your doctor for advice. Q: Can I stop taking NAXDOM 500MG TABLET when my migraine symptoms are relieved? A: No, do not stop taking NAXDOM 500MG TABLET until advised by your doctor. Q: Can I take higher than the recommended dose of NAXDOM 500MG TABLET? A: No, taking a higher than the recommended dose of NAXDOM 500MG TABLET can increase the risks of side effects. If you are experiencing increased severity of migraine attacks which are not relieved by the recommended doses, consult your doctor for re-evaluation. Q: Does NAXDOM 500MG TABLET cause drowsiness? A: Yes, NAXDOM 500MG TABLET may cause drowsiness in some individuals. Have adequate sleep. Do not involve in rigorous activities. Do not interfere with your sleep cycle. Talk to your doctor if the symptom does not improve. Q: How does NAXDOM 500MG TABLET works? A: NAXDOM 500MG TABLET effectively manages migraine, which is commonly associated with nausea and vomiting, by blocking the centres in the brain and stomach that regulate nausea and vomiting. It also increases the contractions and movements in the stomach. NAXDOM 500MG TABLET stops the pain pathways and reduces the release of substances (prostaglandins) that cause inflammation, thus decreasing pain and inflammation. Q: How do you take NAXDOM 500MG TABLET? A: Take NAXDOM 500MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of NAXDOM 500MG TABLET for you depending on your age, body weight and disease condition. Q: Can I take NAXDOM 500MG TABLET if I have lung disease? A: NAXDOM 500MG TABLET should be used with caution in patients with lung diseases such as asthma, other breathing problems, or nasal polyps. Consult your doctor before taking it. Q: Can I take NAXDOM 500MG TABLET during pregnancy? A: NAXDOM 500MG TABLET is not recommended for use in pregnant women during the first 6 months of pregnancy. NAXDOM 500MG TABLET must not be used during the last 3 months of pregnancy. Consult your doctor before taking it.